The “Continental FoF” R&D Project aims to contribute to the advanced of the industry and the technical-scientific community (at national and international level) and enable the total detachment of the factory-floor and the creation of a new advanced and intelligent manufacturing process, in terms of (i) flexibility, modularity and capability of mass customization, (ii) highly efficient digital connectivity throughout the all the facilities’ environment, (iii) dynamic data performance in real-time collection, reading, treatment and interpretation of data, (iv) autonomous and intelligent decision making process, based on artificial intelligence algorithms, (v) Human-Machine symbiosis, (vi) Human-Factory symbiosis and (vii) equally dynamic and interactive logistic processes that assures a full and efficient quality control process at all times.