The talk, entitled “Hybrid neural systems: neuromorphic computing for real-time control of brain activity“, will be given on 15 June at 2:00 pm in room I-105. Henrique Lopes Cardoso (DEI) will chair the session.
Abstract:
The brain is a powerful model for fast, adaptive and energy-efficient information processing. Translating these principles into computing systems is a major challenge with direct relevance for the next generation of intelligent neural interfaces. In this talk I will present work from my research group where we developed a hybrid neural system combining biological neurons with neuromorphic hardware, where artificial spiking neurons process ongoing brain activity in real time. By converting biological signals into spike-based representations, we trained spiking neural networks (SNNs) to identify short-lived electrophysiological patterns and deployed them on neuromorphic hardware. This system was integrated with open-source electrophysiology tools to create a closed-loop pipeline capable of detecting ongoing brain states and triggering targeted stimulation with low latency. Using this approach, we show that hybrid systems linking artificial and biological neurons can support real-time interaction with living neural circuits. These results provide a proof-of-concept for accessible neuromorphic neural interfaces and open new possibilities for adaptive, low-power and biologically inspired computing technologies.
About the Speaker:
Paulo Aguiar graduated in Physics (U. Lisbon, PT), and completed his PhD in Computational Neuroscience at the Institute for Adaptive and Neural Computation (U. Edinburgh, UK). Since 2016, he leads the Neuroengineering and Computational Neuroscience Lab (i3S-UPorto, PT). His group uses a bottom-up approach, focusing on understanding how neural circuits process and store information. The team combines expertise in neurobiology, advanced analytical methods and computational models, to reveal and repair neural function. He has already been the (co)PI/Task Leader in 20+ national and international research projects obtained through competitive calls.








